Histopathological evaluation of collagen fibers using picrosirius red stain and polarizing microscopy in oral squamous cell carcinoma
نویسندگان
چکیده
منابع مشابه
Study of Collagen Birefringence in Different Grades of Oral Squamous Cell Carcinoma Using Picrosirius Red and Polarized Light Microscopy
Objectives. The present study was done to evaluate birefringence pattern of collagen fibres in different grades of oral squamous cell carcinoma using Picrosirius red stain and polarization microscopy and to determine if there is a change in collagen fibres between different grades of oral squamous cell carcinoma. Materials and Methods. Picrosirius red stained 5 μm thick sections of previously d...
متن کاملHistochemical analysis of polarizing colors of collagen using Picrosirius Red staining in oral submucous fibrosis.
BACKGROUND Oral Submucous fibrosis (OSMF) is a common potentially malignant disease, which is characterized by generalized fibrosis of the oral soft tissues. It is due to disproportion in the collagen deposition and degradation. The excess deposition of collagen results in juxta epithelial fibro elastic changes and epithelial atrophy. Neoplastic changes in the epithelium usually precede the cha...
متن کاملComparative Study of Clinical Staging of Oral Submucous Fibrosis with Qualitative Analysis of Collagen Fibres Under Polarized Microscopy
Background & Objectives: Oral submucous fibrosis (OSMF) is a condition where excessive deposition of dense collagen fibers occurred in the connective tissue of oral mucosa. An alteration of collagen necessitates an in depth understanding of collagen in oral tissues as no breakthrough studies have been reported. Therefore the aim was to correlate the clinical, functional and histopathol...
متن کاملClinicopathologic study of a series of giant cell fibroma using picrosirius red polarizing microscopy technique.
BACKGROUND Giant cell fibroma (GCF) is a distinct type of fibroma with characteristic large, stellate mononuclear or multinucleated giant fibroblasts; the stroma of GCF is relatively unexplored. The Picrosirus red polarizing microscopy technique is used to characterize the collagen fibers. The aim of this study was to evaluate the staining properties of collagen fibers in GCF and to correlate i...
متن کاملImmunohistochemical Evaluation of Fascin in Oral Squamous Cell Carcinoma
Background and purpose: Squamous cell carcinoma (SCC) is the eighth most common cancer in men and the fifteenth in women. Localized recurrence and metastasis to regional lymph nodes are major problems in these patients. Fascin is a 55- kDa protein from the family of actin-binding proteins that is expressed in cells with membranous bronchial tubes. The aim of this study was to evaluate the expre...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2015
ISSN: 0973-1482
DOI: 10.4103/0973-1482.154061